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Holy God, Holy Strong One, Holy Immortal, have mercy on us

The trisagion  is a pious and oft-repeated prayer in the Greek liturgy; Goarius correctly observes this in his in notis ad Euchologium, p. 109, in reference to the Mass of St. John Chrysostom. This prayer originated in a miracle which occurred in Constantinople in the middle of the fifth century. Emperor Theodosius, Patriarch Proclus, and all the people were beseeching God on open ground for deliverance from the destruction which threatened them from violent earthquakes. They suddenly saw a boy snatched up to heaven; when he was returned to earth, he reported that he had heard the angels singing the trisagion. At the bidding of the Patriarch Proclus, the whole people sang it with devotion and the terrifying earthquakes ceased, as is related by Nicephorus, bk. 14, chap. 46, and mentioned by Pope Felix III in his third letter to Peter the Fuller (Labbe, Collectionis, vol. 4). This same trisagion is sung in the western church in Greek and Latin on Friday of Holy Week, as Cardinal Bona remarks (Rerum Lyturgicar., bk. 2, chap. 10, no. 5).